Abstract: The antagonistic effect of Lactobacillus against pathogenic bacteria were evaluated in vitro culture of Caco-2 cells. Lactobacilli were added simultaneously with intestinal pathogenic strains (enterotoksihennye
Escherichia coli K88 and Salmonella Typhimurium SARB21 and SL1344), to pathogenic strains and after pathogenic strains for competitive exclusion and displacement analysis. Six lactobacilli significantly limited adhesion and invasion of pathogenic bacteria. In modeling competition and exclusion tests, adhesion of pathogenic strains decreased by strains of Lactobacillus
substantially, and inhibitory effect on the adhesion of pathogenic strains was slightly weaker shift analysis. In addition, we found that the antagonistic effects of lactobacilli against K88, SARB21 and SL1344 were varied. Strain R4 showed a strong brake effect on adhesion to Caco-2 cell K88. The competition analysis in R4, the number of viable cell-related K88 (3. 84 0 10. Log CFU / well) was significantly lower than in the control group without
Lactobacillus (5. 0 02 98. Log CFU / a). Compared with the control group (6. 0 02 07. Log CFU / well), six
Lactobacillus strains all of the strong antagonistic action against SL1344, in particular, D17 showed a higher inhibitory effect on the movement analysis (4. 15 0. 04 log CFU / well). These results assume that strattera 25mg some strains of Lactobacillus >> << can be useful for protection against pathogenic intestinal infections. .
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